ERC analysis of the fly adherens junction now published in PLOS Genetics

Our collaboration with Nathan Clark (Pitt Comp Bio) and Yang Hong (Pitt Cell Bio) is now published in PLOS Genetics! We used Evolutionary Rate Covariation (ERC) analysis to identify proteins with similar evolutionary histories to E-cadherin in the fly:

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007720

The paper was accompanied by a nice Perspective from Colgren and Nichols that talks about using evolution as a guide for cell biology:

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1007937